Ingrid ADRIAANS

In the lab of Rut I will be working on in vitro reconstitution assays with the actin homologue MreB from Bacillus subtilis. My focus will be studying the dynamics and biophysical properties of MreB on Supported Lipid Bilayers (SLBs) using TIRF microscopy.

Adriaans, I. E.*, Hooikaas, P. J.*, Aher, A., Vromans, M. J., van Es, R. M., Grigoriev, I., Akhmanova, A., & Lens, S. M. (2020). MKLP2 Is a Motile Kinesin that Transports the Chromosomal Passenger Complex during Anaphase. Current Biology, 30, 1–10. (*Equal contribution)

Adriaans, I. E., Basant, A., Ponsioen, B., Glotzer, M., & Lens, S. M. A. (2019). PLK1 plays dual roles in centralspindlin regulation during cytokinesis. Journal of Cell Biology, 218(4), 1250–1264.

2020-2023: Postdoc in the team of Simonetta Piatti at the CNRS in Montpellier, unit CRBM, France

Subject: Role of an anillin-RhoGEF complex in the control of septin dynamics during cytokinesis.

2013-2019: PhD candidate in the team of Susanne Lens at the Department of Molecular Cancer Research at the UMC Utrecht, the Netherlands.

Thesis title: A prelude to cleavage: Orchestrating cytokinesis onset in mammalian cells

2010-2012: Master ‘Biology of Disease’ at the Utrecht University, the Netherlands

Master thesis: Aurora B non-consensus phosphorylation during mitosis. Under supervision of Prof. Dr. S.M.A. Lens and Dr. R.C. Hengeveld at the UMC Utrecht.

9 months internship at the Department of Cell Biology, Veterinarian Medicine Utrecht in collaboration with the Hubrecht Institute. Subject: Localisation of endogenous MBK-2 in C. elegans embryos. Examiner: Dr. C. Zijlstra.

6 months internship at the Department of Pathology, UMC Utrecht. Subject: Mouse Mammary Tumor Virus (MMTV) as a causal agent in human hereditary breast cancer. Examiner: Prof. P.J. van Diest.